HbA1c, Homocysteine, Vitamin D Blood Test

The HbA1c, Homocysteine, Vitamin D Blood Test measures three clinically important biomarkers linked to long-term metabolic health, cardiovascular risk, and nutrient status using a simple at-home dried blood spot sample.

This combined blood test includes HbA1c (long-term blood glucose marker), homocysteine (cardiovascular and methylation marker), and 25-hydroxy Vitamin D [25(OH)D] (vitamin D status marker). Together, these biomarkers provide a comprehensive view of cardiometabolic balance and long-term health optimisation.

HbA1c reflects your average blood glucose levels over the previous 2–3 months and is widely used to assess metabolic control and early glycaemic imbalance. Elevated HbA1c levels are associated with increased risk of insulin resistance and long-term metabolic dysfunction.

Homocysteine is an amino acid linked to cardiovascular health, methylation pathways, and B-vitamin status (B12, B6, and folate). Elevated homocysteine may indicate impaired methylation or increased cardiovascular risk.

Vitamin D (25(OH)D) plays a central role in immune regulation, bone metabolism, endocrine function, and systemic health. Suboptimal vitamin D levels are common, even in individuals who supplement.

The HbA1c, Homocysteine, Vitamin D Blood Test allows you to assess these three interconnected biomarkers in one convenient home blood test kit. Results are analysed in certified laboratories, providing clinically relevant data to support personalised nutrition and long-term health monitoring.

Ideal for individuals focused on metabolic optimisation, cardiovascular health, healthy ageing, or proactive nutrient testing.

Frequently Asked Questions

What does the HbA1c, Homocysteine, Vitamin D Blood Test measure?
This combined test measures HbA1c (glycated haemoglobin, reflecting average blood glucose over the past 8–12 weeks), homocysteine (a marker of methylation and B-vitamin status), and 25-hydroxyvitamin D [25(OH)D]. Together they give a focused view of metabolic, cardiovascular, and immune health.

Why combine these three biomarkers?
HbA1c, homocysteine, and vitamin D each capture a different dimension of long-term health risk — blood sugar control, methylation/B-vitamin status, and immune/metabolic function. Suboptimal levels in any of them are associated with elevated cardiovascular and chronic disease risk. Testing them together provides a more complete baseline than any single marker.

Who should consider this test?
It's well suited to anyone monitoring metabolic and cardiovascular health, B-vitamin status, or immune resilience. It's especially relevant for individuals with a family history of type 2 diabetes or cardiovascular disease, plant-based diets, limited sun exposure, or those over 40 focused on healthy ageing.

How is the sample collected?
The test uses a single dried blood spot (DBS) card. A few drops from a fingertip cover all three biomarkers — no venous blood draw or clinic visit required.

Do I need to fast before the test?
Fasting is not required. HbA1c reflects long-term blood sugar and vitamin D testing is also unaffected by meals. Testing in the morning before food or supplements helps ensure consistency for homocysteine.

How accurate is the test?
HbA1c is analysed by high-performance liquid chromatography (HPLC), and homocysteine and vitamin D by LC-MS/MS — the same clinically validated methods used in hospital and research laboratories.

How long does it take to get results?
Results are available 3–5 business days after your sample arrives at the lab.

Where is my sample analysed?
Samples from the Asia-Pacific region, including Australia and New Zealand, are analysed in our accredited laboratory in Australia. Samples from Europe and the United Kingdom are processed in our certified EU laboratory, ensuring all results meet international clinical standards for accuracy and reliability.